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filingDate 2004-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-H2216-H
titleOfInvention Method for testing for bioaccumulation
abstract For use in estimating or predicting bioaccumulation of a chemical analyte, even a surfactant, log P ow values for the analyte may be determined by calculating the log of the ratio of the concentrations of the analyte in n-octanol and in water, equilibrated using a slow-stir method. In this method, samples of the analyte are prepared and stirred in n-octanol and water (or other largely immiscible solvents) at a rate sufficiently low to avoid emulsions over time at a constant temperature. After stirring, the n-octanol layer and the water layer are sampled and the quantity of analyte in each measured.
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