| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-215 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 |
| filingDate |
1984-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1986-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1986-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-H22-H |
| titleOfInvention |
Synergistic effect of chemotherapeutic agents on beta-interferon |
| abstract |
A composition of matter exhibiting a synergistic cytotoxic effect in combination therapy of certain breast cancer and myeloma cell lines is prepared by combining synergistically effective amounts of 5-fluorouracil and human recombinant beta-interferon, optionally together with a pharmaceutically effective diluent or carrier. Preferably the recombinant beta-interferon is a mutein in which the cysteine residue at position 17 of native beta-interferon is replaced by a serine residue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008025948-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005265968-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005226845-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8906162-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7431920-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004247565-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-302928-B6
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005084478-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005118137-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005118138-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006078942-A1 |
| priorityDate |
1984-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |