http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9956191-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5acc73c34cf2b348b8bce69d72b9c37 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 |
filingDate | 2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a06ac2d6bc700ad40d7ade9319b5ee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e3674569d44b6b250d236b7515e27d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8b9aafa5987af3c82e3ef54b1f7d3bb |
publicationDate | 2018-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9956191-B2 |
titleOfInvention | Composition of 5-nitrobenzoate derivatives as anti-metastatic agent that inhibits tumor cell-induced platelet aggregation |
abstract | Disclosed are 5-nitrobenzoate derivatives of Formula I, n nand the preparation method therefor, wherein R is referred to hydrogen (H), unsubstituted, mono-substituted, di-substituted or tri-substituted benzoyl moiety. 5-Nitrobenzoare derivatives of Formula I do not affect the platelet aggregation, possesses the inhibitory activity related to the tumor cell-induced platelet aggregation (TCIPA), and further specifically inhibits podoplanin-induced platelet aggregation. Therefore, 5-nitrobenzoates of the invention are applicable in its therapeutic use as the novel therapeutic agent in preventing tumor metastasis. |
priorityDate | 2012-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.