Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9eceda7a888381343daebf50209b1d84 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96455 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2016-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0da554785c2e517e39628cb3279be460 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87e79b12d896c4a2aab06566f65477ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f86d325676a6da9cb31e6e0e4b3f9697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13a6f5a029a18e8eacead9fa795db093 |
publicationDate |
2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9951390-B2 |
titleOfInvention |
Prostate cancer prognostic compositions and kits |
abstract |
Described herein are method, compositions and kits for prognosis of prostate cancer. The methods include determining the ratio of PCA3 and of a prostate-specific marker expression in a urine sample and correlating the value of the PCA3/prostate-specific marker ratio with the aggressiveness and mortality risk of prostate cancer in the subject. The method for prognosing prostate cancer in a sample of a patient includes assessing the amount of a prostate cancer specific PCA3 mRNA and the amount of prostate-specific marker in the sample; determining a ratio value of this amount of prostate cancer specific PCA3 mRNA over the amount of prostate-specific marker; comparing the ratio value to at least one predetermined cut-off value, wherein a ratio value above the predetermined cut-off value is indicative of a higher risk of mortality of prostate cancer as compared to a ratio value below the predetermined cut-off value. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018223375-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10752957-B2 |
priorityDate |
2004-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |