http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9951374-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 |
filingDate | 2013-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deb123ef39967b73974b14c927fa045d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0976fa422cff142a03cd0ce203adcc75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5924930f3b6a39009875991d3b2ae627 |
publicationDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9951374-B2 |
titleOfInvention | Enhanced throughput mineral coatings for optimization of stem cell behavior |
abstract | Disclosed are methods for cell transfection and regulating cellular behavior. More particularly, the present disclosure relates to methods of non-viral cell transfection and regulating cellular behavior using mineral coatings that allow for the enhanced transfection of cells. The mineral coatings bind polynucleotides and provide a source of calcium and phosphate ions to enhance transfection. The present disclosure also provides a high throughput platform for screening non-viral transfection of cells. The methods of the present disclosure also provide an advantageous polynucleotide delivery platform because the mineral coatings may be deposited on various medical device materials after being specifically developed using the high throughput screening platform. |
priorityDate | 2013-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 425.