Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c6448480b9bc3b0cf72698fb920b773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e62c1f3a97c8eace03a4a3b7d4774bb9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
filingDate |
2014-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b8cae279eb930104fa535cc3baf525f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d6a58f331a2a5dbe1bba8d7936c49b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85813a548877b19544a2c92a1fcec151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a550ee6f2dfb9f4964b8cafaf9f51e35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79f7eb6500c8e5644aa61c0595e4f34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c12f387e394145ecb58f16c45a048289 |
publicationDate |
2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9951050-B2 |
titleOfInvention |
Method of inhibiting DYRK1B |
abstract |
The present invention relates to a DYRK1B inhibitor for use in the treatment of cancer, wherein in said cancer and/or in cells of said cancer the hedgehog signaling pathway is activated, and in particular the activation of the hedgehog signaling pathway is independent of signaling by the G protein-coupled receptor Smoothened. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3906233-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018201606-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10633369-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11547712-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788064-B2 |
priorityDate |
2013-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |