Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16576730e13547067befaa05e2571e43 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-05003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate |
2016-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64a9d0b1e5d4b577e3234c0d5e8a8140 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64cc8fd08100c33013120a59cdb3dc6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efb1e2288ec3c80279d3618cf04862b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90c369baec98501dc8a514fdb4e70274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1add6293216b9114727638e699c78615 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_749199617f59a04cc13c9906d743d549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95330440b38297348019872cf156ebf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e087d2a6aa33f5346b2ba7a006623cd |
publicationDate |
2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9944954-B2 |
titleOfInvention |
Glycerol 3-phosphate dehydrogenase for butanol production |
abstract |
Provided herein are glycerol-3-phosphate dehydrogenase (GPD) enzymes with increased K M for NADH and GPD enzymes with substantially the same affinity for NADH and NADPH and/or are feedback inhibited by glycerol-3-phosphate. Also provided herein are recombinant microorganisms comprising a heterologous gene encoding GPD and a deletion or disruption in an endogenous gene encoding GPD. Also provided are recombinant microorganisms comprising a heterologous gene encoding GPD and a butanol biosynthetic pathway. Further provided are methods of producing butanol comprising providing the recombinant microorganisms described herein and contacting the recombinant microorganism with at least one fermentable carbon substrate under conditions wherein butanol is produced. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541105-B2 |
priorityDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |