http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932322-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c5e77c181522ee1fd44df1ae5ac2196 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 |
filingDate | 2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb86ede8974da540bbd28d277db120de |
publicationDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9932322-B2 |
titleOfInvention | Method for producing sulfonyl chloride compound |
abstract | An object of the present invention is to provide a production method of an intermediate used in the production method of a sulfonylpyrrole compound useful as a pharmaceutical product. The present invention relates to a method of producing sulfonylpyrrole compound (VI) by reacting a pyridine-3-sulfonic acid compound with phosphorus pentachloride in a solvent of chlorobenzene or trifluoromethylbenzene to give a pyridine-3-sulfonyl chloride compound, reacting the compound without isolation with compound (III) to give compound (IV), and subjecting the compound (IV) to a reductive amination reaction. n nwherein R 2 is a hydrocarbon group etc. and R 3 and R 4 are each a hydrogen atom etc.,n n nwherein R 1 is an optionally substituted pyridin-3-yl group, and the other symbols are as defined above,n n nwherein R 5 is an alkyl group and the other symbols are as defined above. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11649206-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11066362-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10570091-B2 |
priorityDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1313.