http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9920372-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92e05c898177243e070bd7aec6381b47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a06f5e335b6d054509abeaac2af845af |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2015-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a65d2cd15390328357130a4095b834fd |
| publicationDate | 2018-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9920372-B2 |
| titleOfInvention | Method for using probe based PCR detection to measure the levels of circulating demethylated beta cell derived DNA as a measure of beta cell loss in diabetes |
| abstract | A method for measuring blood levels of β cell DNA that is released upon β cell death by using a quantitative probe technology to detect amplified methylated and demethylated forms of the insulin gene DNA, representing normal tissue and β cell specific origin, respectively. Using probes permits the sensitive and specific identification of demethylated insulin DNA patterns that are present only in β cells. The method offers a bioassay for detecting β cell loss in diabetes, useful for screening of prediabetes, monitoring of disease progression, and selection and monitoring of therapies. The technique finds potential use in both Type I and Type II diabetes, as well as gestational diabetes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10221457-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10858706-B2 |
| priorityDate | 2012-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 254.