Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89dd7a3a98802fb9d6792c4936c87067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd4800604191832c51ec9b3a4747afff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bd7a45a343acd10e3f5d8775dda2157 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B03C2201-26 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B03C5-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-65 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B03C5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 |
filingDate |
2013-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aad0ff0e00f185f6b1afa800e402a08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33eeb68114f835759a610a6ea90b4fcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c92c5bab63c26a172d9a0c51bc713122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c1a85bbba160628aefb7042d5b039ae |
publicationDate |
2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9915614-B2 |
titleOfInvention |
Microfluidic systems and devices for molecular capture, manipulation, and analysis |
abstract |
Methods, systems, and devices are disclosed for molecular capture, manipulation, and analysis. In one aspect, a device to aggregate and characterize particles in a fluid includes an electrically insulative substrate including a channel to carry an electrically conducting fluid containing particles, electrodes located in the channel forming a nanoscale opening and including an insulating layer over their surface at the opening, a first circuit to apply a non-uniform ac electric field and a dc bias signal across the electrodes, in which the applied non-uniform ac electric field produces a positive dielectrophoretic force to aggregate the particles in a trapping region including the opening and adjacent region, a second circuit to detect changes in a dc current caused by at least some of the particles in the trapping region, and an optical device that directs a coherent light beam on the opening to determine Raman spectra of the particles in the trapping region. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10534355-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018025951-A1 |
priorityDate |
2013-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |