| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5db5982658b38e67f0569415a6b9ea3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb351a5a4e03ee3773bd0df5dbae9ac3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4626a2a79d0d2572e83fcf56caa84a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2304e8417060cea10c40466801fed62c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa51d5049961579867b60eee5f446bd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c6bc29e73fa76805473ddb55ae9060c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6408414759c08af13f73bff1fdccee6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e3c9a9b161805442f89a4bea490b8ae |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-125 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 |
| filingDate |
2015-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_744058251f3bc17b837ac2f009fca341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4baa7521f75b96093c926480d3c45a2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d68abc01668c05200a22439ac9392e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d7d3d0dd3751a5a188cadb9213f0f5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3371a221aea78746e3443d64ed3bca38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a921c1e4ead50de2f5a9239b925c18a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c13f1ad6a2a1f0c0996fc881fbf05e0 |
| publicationDate |
2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9914949-B2 |
| titleOfInvention |
Method for enhancing N-acetylglucosamine production through glcK knockout of Bacillus subtilis |
| abstract |
The present invention provides a method for enhancing N-acetylglucosamine production by usage of a recombinant Bacillus subtilis with a glcK knockout. This invention enhanced the production of GlcNAc by knocking out the glcK gene which encodes a glucokinase, thus eliminating the GlcNAc phosphorylation to GlcNAc-6-P. The specific growth rate and content of GlcNAc in the supernatant of the recombinant Bacillus subtilis with the glcK knockout were 0.15 h −1 and 3.0 g/L, respectively, which were 2.32 times and 2.14 times of those of the control strain without glcK knockout. The recombinant Bacillus subtilis of the present invention would be potentially useful for industrial production of GlcNAc. |
| priorityDate |
2015-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |