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filingDate 2016-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9903804-B2
titleOfInvention Real-time label-free high-throughput cell screening in flow
abstract A label-free imaging-based flow cytometer that measures size and cell protein concentration simultaneously is disclosed. Cell protein concentration adds a parameter to cell classification that improves the specificity and sensitivity of flow cytometers without the requirement of cell labeling. The system uses coherent dispersive Fourier transform to perform phase imaging at flow speeds as high as a few meters per second. To retrieve cell information in real-time, an analog signal processing system based on quadrature phase demodulation is described.
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