Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_930dbfaf9af0027ba4121c0a7c4288de http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ae7bc470b590116f17769a5b53f38cc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88 |
filingDate |
2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db583545bab8c2730772a189bc67677c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9314b9d1aa160bb817e669bca40bb12c |
publicationDate |
2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9890391-B2 |
titleOfInvention |
RNA vector with an open reading frame, an albumin 3′-UTR, and a histone stem loop |
abstract |
The invention relates to an artificial nucleic acid molecule comprising at least one open reading frame and at least one 3′UTR element comprising a nucleic acid sequence which is derived from the 3′UTR of an albumin gene or from a variant of the 3′UTR of an albumin gene. The invention further relates to the use of such an artificial nucleic acid molecule in gene therapy and/or genetic vaccination. Furthermore, the invention relates to the use of a 3′UTR element comprising a nucleic acid sequence which is derived from the 3′UTR of an albumin gene or from a variant of the 3′UTR of an albumin gene for the stabilization and/or prolongation of protein expression from a nucleic acid sequence comprising such 3′UTR element. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898589-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018177894-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11739125-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11761009-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11760992-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11661634-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667910-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786590-B2 |
priorityDate |
2012-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |