Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6298136e040a9b9cd147a4a7b3220ab1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8902b26da143e3ca1c4eeb1a8843690 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a1501f734e48026310aaa43462f8c57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59919a56f27d4169b3b2616033da5119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7436435a1c5fa748c1ac9cfa5e0f6bde |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
filingDate |
2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2190a7af0907f7b6e95daf809adcc90d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed42a73aa63cfec3422205ac2fc660e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5b36b1206d07963ec898204f723ef88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaf78530df4f95209261dd188181f48b |
publicationDate |
2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9879330-B2 |
titleOfInvention |
Hepatitis B variants with reduced sensitivity to therapeutic compounds, their detection and uses thereof |
abstract |
The present invention is a diagnostic kit and materials for: 1) the prediction of the long-term response of a chronic hepatitis B virus (HBV) carrier to treatment with nucleoside/nucleotide analog, or their combination; 2) the detection of HBV variants that exhibit reduced reactivity to antibody detection; 3) the detection of HBV variants in the precore/core region that negatively affect the course of liver disease; 4) the identification of the HBV genotype. |
priorityDate |
2008-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |