http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9873689-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_883379d81fab4a6bec98bf7fc2db6b7c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 |
filingDate | 2015-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1b4a63fae5195f91ecfb284ec950063 |
publicationDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9873689-B2 |
titleOfInvention | Synthesis of fatostatin based polycyclic compounds |
abstract | The present invention relates to methods and strategies for large-scale synthesis of compounds having the chemical structure: n nThe R substituents are H, methyl, isopropyl, benzyl, cyclohexyl, cyclopropylmethyl, methoxy, tert-butyloxycarbonyl, methanesulfonyl, p-toluenesulfonyl, quinolinesulfonyl, or thiophenesulfonyl groups. The method comprises condensing prothionamide with a halo nitroacetophenone to form a nitrophenyl substituted thiazole, reducing the nitro group to form an amine and derivatizing the amine to produce the compound. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11339142-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497738-B2 |
priorityDate | 2014-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.