Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-401 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 |
filingDate |
2015-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9154c7b5c6631c654d163fc96674d48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccdd5a73695a01a23aaf95c8be0cc2ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03a05a0216066631e1286d0e2b9164af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79cf9f17b53b1813b33f9c1891ae9c5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c09591711819fbd6ebb81bd7f7ecde8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3284f300d0af4e633b2a47726d1fa3b |
publicationDate |
2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9862720-B2 |
titleOfInvention |
Inhibitors of the renal outer medullary potassium channel |
abstract |
The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208064-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160751-B2 |
priorityDate |
2014-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |