http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9862712-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 |
filingDate | 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85bf1f97ae00dbe7f13022f732fbbb0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3370cbc739330c66ad238ed767f8ca30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16e40811dbb233df09c24cff1440cf7a |
publicationDate | 2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9862712-B2 |
titleOfInvention | Benzimidazole based EGFR inhibitors |
abstract | The present invention disclosed a novel EGFR inhibitor compound of formula (I), process for preparation thereof and methods of treating abnormal cell growth in mammals by administering the compounds of formula (I). n nWherein, R═—H, 3-CH 3 , 4-NO 2 , 4-Cl, 2-CH 3 , 4-CH 3 , 4-Br, 4-Fn nR 1 ═—H, -4-OCH 3 , -4-NO 2 ,-2-NO 2 , -4-Cl, -2,4,6-CH 3 , -4-CH 3 , -2-F,4-Br, -4-CF 3 , -4-S—CH 3 , -4-Cl,-3-CF 3 , -3-S—CH 3 , -3,5-CF 3 , -2-S—CH 3 , -3-CF 3 ,-4-OCF 3 , —Si—(CH 3 ) 3 , —Si—(C 2 H 5 ) 3 , (CH 3 ) 2 —Si— C 2 H 5 . |
priorityDate | 2014-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 242.