Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a0c5fbebb6d691211eb677e85bd9bfb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 |
filingDate |
2013-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_237f8bdd4097fdf6f4ade94db7babcaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48db3485fb04e6d9730cfad0fccd5147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48e3c26a06378ba275af991179e5f4c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_773aca11917b37d7148f62c942af2c7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640a17f56c4e5d2d56737056fc59eae6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c8f6110ff0562c4dae7ab8b79657bb7 |
publicationDate |
2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9844610-B2 |
titleOfInvention |
Method for preparing in situ-formed hydrogel using enzyme-immobilized support, and biomedical use thereof |
abstract |
The present invention relates to a method for preparing a hydrogel, including the steps of: preparing an enzyme-immobilized support; making contacting with a polymer having a phenol or aniline functional group at a side change and the support in the presence of hydrogen peroxide to cross-link the same; and obtaining a hydrogel by separating the enzyme-immobilized support. According to the present invention, a hydrogel is formed by cross-linking a polymer having a phenol or aniline functional group at a side chain through an enzyme-immobilized support, and thus a hydrogel containing no enzymes is obtained. Therefore, the biomedical application range of a hydrogel can be expanded since it is possible to overcome an in vivo safety problem such as immune reaction caused by an enzyme. |
priorityDate |
2012-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |