| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8ca81d100702fe0f596b23c38fd581c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe2fac2b804584e44e9701dfcb0c82cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb8ea1464c6e96bb546b7e6859e96302 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-055 |
| filingDate |
2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7193a781f26b8d7f662a6945e65823a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e26cbdafc8a4cb860739bfa30a506e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89d20c623973cae2e4e760eb043a683d |
| publicationDate |
2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9844519-B1 |
| titleOfInvention |
Method of treating TDP-43 proteinopathies using hexachlorophene |
| abstract |
A method of treating TDP-43 proteinopathies such as Alzheimer's disease, amyotrophic lateral sclerosis, and fronto-temporal lobar dementia is presented herein. It was found that administering hexachlorophene to cells expressing endogenous TDP-43 or overexpressing wild-type TDP-43 reduced accumulation of TDP-43 in the cells. |
| priorityDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |