| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J3-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48061 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 |
| filingDate |
2016-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_809f9d7ca331206051b382f37d887de6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93582c7ce0d8b00e903aedef5bc93763
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d74160d8b4f18a8e6bf882959221ebb |
| publicationDate |
2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9821068-B2 |
| titleOfInvention |
Methods to induce targeted protein degradation through bifunctional molecules |
| abstract |
The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to methods for the targeted degradation of endogenous proteins through the use of the bifunctional compounds that link a cereblon-binding moiety to a ligand that is capable of binding to the targeted protein which can be utilized in the treatment of proliferative disorders. The present application also provides methods for making compounds of the application and intermediates thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11318205-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779578-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11028089-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11059801-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11485743-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591332-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11117889-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11623932-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020191377-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512080-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11292792-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11679109-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685750-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11583586-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11707457-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723980-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11746120-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10874743-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019315753-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11485750-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019118893-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10787443-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352350-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291732-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11358948-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019151457-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11642413-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667628-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11752197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10239888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10849980-B2 |
| priorityDate |
2014-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |