| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_937da8a34db452f2c779f1a8f4c0bc58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c08768e296cc175cd6e151125525b5ac |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-72 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate |
2013-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc8dfe3920ccabf22711918df513c0c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9088f85444274c380187cf9fd7d5bd2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e93377dd5d93b38ec12708756b4d51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d03f7a5d4d899589bcb96f0d6e4ce976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c25e8b64ee77cc0a8833329440a3f4d |
| publicationDate |
2017-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9797901-B2 |
| titleOfInvention |
Sensitive and rapid methods of using chimeric receptors to identify autoimmune disease and assess disease severity |
| abstract |
The present invention provides methods and compositions useful in the diagnosis and management of autoimmune diseases. In particular, the present invention provides improved methods and compositions for the diagnosis and management of Graves' disease. The methods of the present invention not only avoids the need for radioactivity and are much simpler, economical, and rapid than methods traditionally used for the diagnosis of Graves' disease, but also improve upon the sensitivity and detection abilities of previous luciferase-based autoantibody detection assays. Such improvements are based upon the superior performance of assays comprising a chimeric TSH receptor in the presence of a glucocorticoid including, but not limited to, dexamethasone. |
| priorityDate |
2000-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |