| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8f435d057decdd2fd8f14fe32e38853
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f39b7232d5a1b5f2c5cf7d8e56c64e7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_644390bf2f9aa3a7d6cc85232c37549b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c90f4702549fb2dce6423ef9b3a96f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4492c2f1ee6b23b28f618989f19f878f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e48b5048e24bcc05dfcbba9e713dbc2b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3181
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3527 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2016-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92735a7f61df56928dfa9793a1ad97ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8af902ccc68984c5435ebbc5a04fa0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e52d11cb188748ad06ad1f7fc022a0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59f70faf0c267efe6313d9a65cf5742c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baf05b638281192f11bdc90b2bf3d3a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e43de14018404bdf6f53aef634410ab2 |
| publicationDate |
2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9790500-B2 |
| titleOfInvention |
Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer |
| abstract |
Provided herein are compositions, method and uses for modulating IAP activity or for the treatment of cancer. The compositions comprise dual-targeting antisense oligonucleotides (dASO) for administration to a cancer cell, wherein the cancer cell may be characterized by elevated expression of one of more of BIRC6, cIAP1 or survivin. The cancer may be selected from one or more of: prostate cancer; childhood de novo acute myeloid leukemia; colorectal cancer; neuroblastoma; melanoma; and non-small cell lung cancer. The prostate cancer may be castration-resistant prostate cancer (CRPC). |
| priorityDate |
2015-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |