| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e811f883bfbdb741e5b7a412f38d22e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6997c68f2c2ff63addd4f6d2a104a34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d304f6bb4e2909cfa10a856d65280d24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28ebfce59d04df499e4b3f9ba6cde9aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f63d931ceac0501d4ceb83f5a7fd9d7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L2666-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F293-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F4-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F293-00 |
| filingDate |
2012-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a1721ede3458b6efb3f30e73093cdb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9241a9bfbb79c89abfc48b71dd437603
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab6cc4357ca40af3939384ee7f6e6b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c17dcf6d13cb1608a16ef5a1a2ffd2e9 |
| publicationDate |
2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9765213-B2 |
| titleOfInvention |
Drug carriers comprising amphilphilic block copolymers |
| abstract |
An aqueous composition comprises an amphiphilic block copolymer, having a hydrophilic block comprising pendant zwitterionic groups and a hydrophobic block, and a biologically active compound associated with the polymer. The polymer is preferably in the form of micelles, and preferably the biological active is a hydrophobic drug. The hydrophilic block is preferably formed from acrylic monomer including phosphorylcholine groups. The hydrophobic group is suitably formed from monomer which has groups which can be ionised at useful pH's, especially tertiary amine groups. Micelles may be formed by dissolving the block copolymer in aqueous solvent at a pH at which the amine groups are protonated then raising the pH to a value at which the amine groups are substantially deprotonated, whereupon micelles spontaneously form. The preformed micelles are then contacted with active, under conditions such that solubilisation of the active occurs. The active may be for tumour treatment. |
| priorityDate |
2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |