Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1c43a1edbed2f4cce803c2ba180f1ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8abb210936dc3b56af93e346a2335b7f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 |
filingDate |
2015-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00ff9a96efde1c31350ec367f94d89e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1c083e058431a0d9bc32241c528ee67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca536b833ace7820d27162ccb66cef3d |
publicationDate |
2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9765106-B2 |
titleOfInvention |
Neisseria gonorrhoeae therapeutic based on CMP-nonulosonate sugars |
abstract |
N. gonorrhoeae has become resistant to almost every conventional antibiotic. Described herein is the use of CMP-nonulosonate analogs to counter gonococcal complement evasion. The nonulosonate sugar is incorporated into the lipooligosaccharide of the N. gonorrhoeae which in turn reduces the serum resistance of the bacteria. This provides a novel therapeutic strategy against the global threat of multi-drug resistant gonorrhea. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018235989-A1 |
priorityDate |
2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |