Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd47318319f20f7f99d9fef1fd3e511b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate |
2014-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6fd0de2b7aa6c29984e8f715e9b4653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7807ea38197b9fcb2669a2cf52eb06e1 |
publicationDate |
2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9724354-B2 |
titleOfInvention |
Combination of catalytic mTORC1/2 inhibitors and selective inhibitors of Aurora A kinase |
abstract |
Disclosed are methods for the treatment of proliferative disorders. Disclosed in particular, are methods for treatment of proliferative disorders such as cancer, by administering an mTORC1/2 inhibitor in combination with a selective inhibitor of Aurora A kinase. Preferred MTORC1/2 inhibitors include MLN0128 and the preferred Aurora A kinase inhibitor of the combination is MLN8237. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352361-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020146779-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11548896-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10954241-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844067-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11680068-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11661423-B2 |
priorityDate |
2013-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |