| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b36e802ae3429bbce43513b03fc1419a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_997e596ae88a827b95cb08d53eb20b0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5b0c14edc6cb1532902fdd3dca7396f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d32d54bdf6b24bb21d4485a98de6bb9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a621367bfd1209c45f9cc94846b56fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2239ad5ac9b02f8fc52214ff254915d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0008 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0448
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0492
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0613 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-06 |
| filingDate |
2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b121bdbbff5ac351b55b02be74304afe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d261033ab843a665ef979953d6ba572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c282255f09198bf6c3a2c7380e21bc51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f987feea000be60c6cdb74b1b0c472e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebae57128920341a90e7777d5ba7fac1 |
| publicationDate |
2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9700456-B2 |
| titleOfInvention |
Device and method for corneal delivery of riboflavin by iontophoresis for the treatment of keratoconus |
| abstract |
Ocular iontophoresis device and method for delivering any ionized drug solution to the cornea includes: a reservoir containing a solution suitable to be positioned on the eye; an active electrode disposed in or on the reservoir; and a passive electrode suitable to be placed on the skin of the subject, elsewhere on the body; elements for irradiating the cornea surface with suitable light for obtaining corneal cross-linking after the drug delivery; wherein the reservoir and the active electrode are transparent to UV light and/or visible light and/or IR light. The method includes: positioning the iontophoretic device on the eye to be treated; driving the solution by a cathodic current applied for 0.5 to 5 min, at an intensity not higher than 2 mA; and thereafter irradiating, with UV light for 5 to 30 min at a power of 3 to 30 mW/cm 2 ; thereby obtaining the corneal cross-linking of the solution. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497766-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11135090-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729716-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11033429-B2 |
| priorityDate |
2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |