http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9669000-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b55163625f7ddff7e523071e11b9c6fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 |
| filingDate | 2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fb83bd8dc9584f5aa233d3f7b9ceac3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10b1fb9ba1ac10e8b6deabc275006988 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79c576d1a5dcbf56668601509280da7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57189ed7e058acec133199cf775c8db5 |
| publicationDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9669000-B2 |
| titleOfInvention | Pharmaceutical compositions comprising lignans and their derivatives for treating hyperplastic diseases |
| abstract | The present invention relates to a pharmaceutical composition comprising specific compounds which may be obtained from Leontopodium alpinum Cass. (Edelweiss). A preferred compound is leoligin (=(2S,3R,4R)-4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrofuran-3-yl]methyl(2Z)-2-methylbut-2-enoat]). Corresponding means and methods in respect of medical uses of the compounds are described. The present invention also provides a medical device comprising, containing or having been contacted with the compound. The compounds provided herein may particularly be used in the treatment of hyperplastic diseases, in particular intimal hyperplasia, e.g. stenosis, restenosis, atherosclerosis and the like. Also envisaged herein is the use of these compounds in the treatment of proliferative diseases, such as leukemia, prostate cancer and lung cancer. |
| priorityDate | 2008-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 463.