| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94e0f6a427afa8ada0c36d33f08ee095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0c0e335601028b676b2be4849cbf640
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fb100a7b8920d27e6856ae802c449a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a6cbab5c28eac03af3e6d228ad48968 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2013-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bccf11b793d73f58f9178cf2dde8f862
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_674a8ff8d7233dee6276e35219c5c91f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f2ba4d21c5cdf04e97628806aba1f14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e957b6510adc017e4d9092503309238 |
| publicationDate |
2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9663797-B2 |
| titleOfInvention |
Optimized expression cassette for expressing a polypeptide with high yield |
| abstract |
The present invention is based on the finding that the combination of a specific 5′UTR polynucleotide sequence (see SEQ ID NO 1) and the hCD33 secretory leader sequence in an expression cassette for expressing a polypeptide of interest results in a surprisingly better expression level of the polypeptide of interest compared to prior art expression cassettes. Based on this finding, the present invention inter alia provides novel expression cassettes, expression vectors and methods for producing a polypeptide of interest with high yield. |
| priorityDate |
2012-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |