| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4001b09828b1f5e569b14f8798768217
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a79c92ff79703cf47ce8de2a362bb9cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e7d5c58fa757b7b1bb853b1fab97ea7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0751969d60a32294ce28c80d070f1515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ade7d9295c71adc600a07d9842398e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53db80498433e8bcc947e9f0761a6580 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-12 |
| filingDate |
2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5259fb30b5866bcaa6431773f5e0ba3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2afb9b889837ea712226a48c58b8f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_388e6ea799d627dac1a14baabe152468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09358a93d18eac83cfa25493814fdd11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c45419ca3c3b7485209a8f1bda76a4b |
| publicationDate |
2017-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9657263-B2 |
| titleOfInvention |
Pharmaceutical composition for inhibiting infection and replication of influenza A and B virus, and the manufacture thereof |
| abstract |
Disclosed is a pharmaceutical composition for inhibiting infection and replication of influenza A and B virus, and the manufacture thereof. The pharmaceutical composition is produced by a manufacture of low-temperature disintegrating cyanobacteria, comprising the steps of: (a) mixing cyanobacteria and non-organic solvent to form a suspension containing cyanobacteria; (b) freezing the suspension with a temperature below 0° C. to form a ice block and the ice block being melted at a low temperature, the whole step being repeated at least twice; (c) separating the cyanobacterial residues and extract solution of the suspension; and (d) collecting the isolated cyanobacterial extract solution; wherein the cyanobacterial extract solution is a solution containing cyanobacterial bioactive substances. The pharmaceutical composition is able to effectively inhibit binding of sialic acid and hemagglutinin of influenza A and/or B virus, so as to inhibit infection and replication of influenza virus. Further, this pharmaceutical composition is able to inhibit infection of influenza virus resistant to neuraminidase inhibitors. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11246898-B2 |
| priorityDate |
2010-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |