http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9645135-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a79dd752ce215a937d767f7ac35b698 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fd29e93dafcecd33e11d38df288d2cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-4146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01L29-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L29-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 |
| filingDate | 2011-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ced3867e1d9a3029e1de9860c214b2f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_598c9f531e4d4a4bcb0dc19180042621 |
| publicationDate | 2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9645135-B2 |
| titleOfInvention | Nanowire field-effect transistor biosensor with improved sensitivity |
| abstract | The present invention is directed to a multiwire nanowire field effect transistor (nwFET) device for the measurement. The device includes a sensing nanowire having a first end and a second end and a nanowire FET having a first end and a second end, wherein the first end of the sensing nanowire is connected to the nanowire FET to form a node. Additionally, the first end of the nanowire FET is connected to a source electrode, the second end of the nanowire FET is connected to a drain electrode, and the second end of the sensing nanowire is connected to a base electrode. The sensing nanowire is derivatized with a plurality of immobilized capture probes that are specific for a target(s) of interest. The device is used to detect biomolecules or to detect the change in the ionic environment of a sample. In a further embodiment, the sensing nanowire is derivatized with amino, carboxyl or hydroxyl groups. Upon a change in ionic environment, or binding of a molecule to the sensing nanowire, the sensing nanowire current (I B ) fluctuates. This fluctuation is amplified and readout as the nanowire FET drain current (I D ). Accordingly, the present invention provides for label-free detection of biomolecules and may find use as a point-of-care diagnostic device. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10968098-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10378044-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11169151-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11143584-B2 |
| priorityDate | 2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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