Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72d118f5664072de841f9c5c34b9d99 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0681 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L7-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2013-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf41f0bcd86bb9b45c143647592a2943 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0111baf8d6ee5bf6e87222c23e3072d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_343aa34ba37b58be4f3be7d98254a8d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d03b95cf6400aa02a4ba88edc00e245b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15aa491f59f0b61b30ff11de2221a67c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_748540162a3e7edd75199ea3d714e433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_834f8a3a157c76d7c1634340a0e4d638 |
publicationDate |
2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9644232-B2 |
titleOfInvention |
Method and device for collection and amplification of circulating nucleic acids |
abstract |
Provided herein are methods for the collection and amplification of circulating nucleic acids from a non-cellular fraction of a biological sample. Circulating nucleic acids are extracted from the non-cellular fraction and are circularized to generate single-stranded nucleic acid circles, which are then subsequently amplified by rolling circular amplification using random primers to produce an amplified library. Devices for the collection of a non-cellular fraction from a biological sample are also provided. The device includes a filtration membrane and a dry solid matrix, which is in direct contact with the filtration membrane. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10655167-B2 |
priorityDate |
2013-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |