Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18677043f445e94d142021f69d4a683d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60e8e0ebf37cbc01d162ce679f192fab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9598f5041ee8471718cb80f7c54fc359 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6af805cca1f89891f07db052c0620fd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54ae5e452ed609179e635c91ad116e6a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2549-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-301 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2013-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ae005a5612fc40c114a8443e11266f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bc9fe68cc389ac822f57febc19eb380 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85af20e82e19fcbe7526f1c7ed7e01b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360e720c9c6137c8f0f4d3d7420344ee |
publicationDate |
2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9644198-B2 |
titleOfInvention |
RNase H-based assays utilizing modified RNA monomers |
abstract |
The present invention pertains to novel oligonucleotide compounds for use in various biological assays, such as nucleic acid amplification, ligation and sequencing reactions. The novel oligonucleotides comprise a ribonucleic acid domain and a blocking group at or near the 3′ end of the oligonucleotide. These compounds offer an added level of specificity previously unseen. Methods for performing nucleic acid amplification, ligation and sequencing are also provided. Additionally, kits containing the oligonucleotides are also disclosed herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10988760-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299730-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557133-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10246705-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11319534-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10457936-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149310-B2 |
priorityDate |
2008-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |