Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_452edf09f236371e61e3fd22a06ded78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a66011e0183df82faf7e500f7ee7aa4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5110802ea2725299d128970b5f7db6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_299129fa389588e95826e37a6c408757 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-107 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2011-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4539722c937f004abb769c17044c70f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a661e5a244e6df21c4d9e12bf38ae1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d338c21c515d343a4347b7e94e99c84 |
publicationDate |
2017-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9637790-B2 |
titleOfInvention |
Detecting mutations in DNA |
abstract |
Provided herein are methods for detecting mutations in nucleic acid, and compositions and kits for performing such methods. In particular, nucleic acid amplification and fluorescence detection methods are provided to detect mutations and assess the mutational load. The methods are based on a set of adjacently binding probes wherein one probe is labelled with a quencher and the other is a self-indicating probe labelled with fluorophore and quencher. The binding of the probes is analyzed by melting curve analysis. |
priorityDate |
2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |