| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1de6cee02d67397ca27259eb779db35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_408a10fa692f630c7438b40989537197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67660d2be72351c23fcf789fa3b34e15 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2013-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8680c8397c2a73cb471f2a92092fb6d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81f43d730a6ed87e5bb5d810a2aaf777 |
| publicationDate |
2017-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9624549-B2 |
| titleOfInvention |
Stable gene targets in breast cancer and use thereof for optimizing therapy |
| abstract |
A method for determining genes in breast cancer that are stable in copy number, expression and sequence in tumors from nearly all patients. Certain stable genes are targets of standard chemotherapy. The effectiveness of therapies that act upon these targets depends on maintaining the stability and integrity of these genes in tumors. Mutations in these targets result in poor response to therapies that target these gene products. In the instant invention, ordinarily stable gene targets are characterized as either normal or mutant for the purpose of determining whether to include or exclude particular drugs as potential treatments. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11454630-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020172296-A1 |
| priorityDate |
2012-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |