| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b4ee13af463c18c765406625e1c5d44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14c17af478d9bb7d7c293b10a5ae8c0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e557b3eda09134be9bd18bd3b049d641
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d37b86da5e841e16c1a2711ac6144433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6ffb51bba8325290a508724dea6f226 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2871
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2014-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4733500c110940a1f5e71a740620be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2701c746aed13dd5f4248b5a6dc87286
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360ec71d4658932d9d9ab44b468aad3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_612240bc8f80f7fe06f85e9d2eee2fba |
| publicationDate |
2017-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9599625-B2 |
| titleOfInvention |
Blood biomarker for early blood brain barrier disruption in ischemic stroke |
| abstract |
Methods and apparatus for determining blood brain barrier (BBB) damage and treating patients who may have suffered from BBB damage due to an ischemic event are provided. The methods and apparatus involve detecting the presence of cleaved occludin fragments in a sample of blood. According to some embodiments, the method further provides determining the degree of BBB damage based on the concentration of occludin fragments in the sample. In further embodiments the present disclosure provides kits for detecting the presence of occludin fragments in a blood sample. |
| priorityDate |
2011-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |