Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50a09e48366aa06b1a5cddf4a655fc7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_763fc0113ef73f5c7fa40bd6b8453ba0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_549dbe9b422ebcfdf5a9662843e4c411 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d0adc65fc3573df1ef508b77178c65e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-2207 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52 |
filingDate |
2012-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1a47deb9c2840a546f82d51eca3ff4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d9cc6bc6991f2b7ba85856f1f7fd001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c99fb2cfdd4dfc5489a373d6a95e6b83 |
publicationDate |
2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9588110-B2 |
titleOfInvention |
Multi component antibody based detection technology |
abstract |
The disclosure provides methods for detecting the concurrent presence of at least two targets within a biological sample. The method includes contacting said biological sample with a first binding agent, said first binding agent operably linked to a first sortase molecule, wherein said first binding agent specifically binds to a first target; contacting said biological sample with a second binding agent, said second binding agent operably linked to a first sortase recognition sequence peptide, wherein said second binding agent specifically binds to a second target; adding a sortase substrate under conditions where a first sortase-mediated ligation of the sortase substrate to the first sortase recognition sequence will produce a ligation product, and detecting the ligation product, wherein detection of said ligation product indicates the concurrent presence of the first target and the second target in the biological sample. Also disclosed are kits comprising reagents for performing the methods as claimed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766923-B2 |
priorityDate |
2011-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |