| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1763f7f78d01cad638210d060676591a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487 |
| filingDate |
2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79a7a3b7d8763dbbccf18fa15231806d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f8cbb71029e6c8b11abe051f964d7c2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74aa3feb8b7d7875e85f03751f3f6661 |
| publicationDate |
2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9574228-B2 |
| titleOfInvention |
Nanopore-facilitated single molecule detection of nucleic acids |
| abstract |
The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034996-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124827-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10816537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10317392-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10273527-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11531021-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018093976-A1 |
| priorityDate |
2010-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |