Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate |
2015-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2978c78e9d93b91dea0dfa2ea2115dc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7839f42fae630575a69bfaff49768556 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be6cf547dd516b5a253834930ce228fe |
publicationDate |
2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9541546-B2 |
titleOfInvention |
Method of promoting excitatory synapse formation with an anti-Ephexin5 phospho-Y361 antibody |
abstract |
The invention provides methods of screening a compound that can increase spine/excitatory synapse formation and/or numbers. The compound is identified by contacting Ephexin5 with a test compound and selecting the compounds that inhibit Rho GEF activity of Ephexin5. Additionally, the invention also provides methods for increasing spine/excitatory synapse formation and/or numbers by contacting a neuron with an Ephexin5 inhibitor. |
priorityDate |
2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |