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filingDate 2015-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae5f3f1b7851b96df7a44631f8315225
publicationDate 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9540660-B2
titleOfInvention Vector comprising multiple homologous nucleotide sequences
abstract The invention relates to vectors comprising two or more homologous nucleotide sequences and methods for generating them. The invention concerns substituting bases in the homologous nucleotide sequences with different bases that do not alter the encoded amino acid sequence. The invention allows for the reduction of intramolecular recombination between homologous nucleotide sequences, in particular in mammalian cells. The invention further relates to nucleotide sequences containing substituted bases.
priorityDate 2008-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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