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filingDate 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51d63219425f8a709c31c4f5a1a9afdd
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publicationDate 2017-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9534253-B2
titleOfInvention Base-by-base ratcheting of DNA/RNA in a Y-shaped nanochannel
abstract A mechanism is provided for ratcheting a double strand molecule. The double strand molecule is driven into a Y-channel of a membrane by a first voltage pulse. The Y-channel includes a stem and branches, and the branches are connected to the stem at a junction. The double strand molecule is slowed at the junction of the Y-channel based on the first voltage pulse being weaker than a force required to break a base pair of the double strand molecule. The double strand molecule is split into a first single strand and a second single strand by driving the double strand molecule into the junction of the Y-channel at a second voltage pulse.
priorityDate 2012-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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