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filingDate 2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4179bb8d3a9b067d19bd4d7937e802e3
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publicationDate 2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9528119-B2
titleOfInvention Transgenic cells with increased plastoquinone levels and methods of use
abstract Disclosed herein are transgenic cells expressing a heterologous nucleic acid encoding a prephenate dehydrogenase (PDH) protein, a heterologous nucleic acid encoding a homogentisate solanesyl transferase (HST) protein, a heterologous nucleic acid encoding a deoxyxylulose phosphate synthase (DXS) protein, or a combination of two or more thereof. In particular examples, the disclosed transgenic cells have increased plastoquinone levels. Also disclosed are methods of increasing cell growth rates or production of biomass by cultivating transgenic cells expressing a heterologous nucleic acid encoding a PDH protein, a heterologous nucleic acid encoding an HST protein, a heterologous nucleic acid encoding a DXS protein, or a combination of two or more thereof under conditions sufficient to produce cell growth or biomass.
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