Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bddd83b0d4337e850c8a5e184ed0ec20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-02006 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
filingDate |
2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c9076a810da23896b9a92b728f310e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c6d6fa95e420cd96c5718774b763944 |
publicationDate |
2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9523084-B2 |
titleOfInvention |
Phosphodeoxyribosyl transferase mutant enzymes and uses thereof |
abstract |
The present invention relates to enzyme mutants obtained from the nucleoside deoxyribosyltransferase (NDT) of Lactobacilli bacteria. These mutants are surprisingly able to exchange deoxyribose mono-, bi- and triphosphate between various nucleobases. In vitro syntheses have been successfully performed with several nucleobase analogs. These enzyme mutants provide new tools to synthesize, in vitro and/or in vivo, dNTPs or analogs thereof. |
priorityDate |
2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |