Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a6911fbf1d120a893f2fdc32c17cc3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afbf74f1f21f29cab72c82a61e54284e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_352dcc674cada600c94b4144b9eaa99b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b13a60dc19709f8ea947dbf08cc2fd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ae82682fcc04063d83ca293ec8c2b54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41abe8307a25c6e8f0997e9e7f098670 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7416d81e903982c257c558ee95ef59c0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f05e7a808867740b5f96faa2c4745ec2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e7c6c6a684be05f7ae7d789bb003524 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2b3bb37ae0930447c7e7ffdf99c6627 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e653126345fcb1852e5bbb934ca2495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d96d059edeaa4e888e77b1ee62dbc49f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48432bb528faf18eff620bf7011660c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd9ddce0de96f9e665c8ad16aa561675 |
publicationDate |
2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9506926-B2 |
titleOfInvention |
Molecular predictors of therapeutic response to specific anti-cancer agents |
abstract |
Herein is described the use of a collection of 50 breast cancer cell lines to match responses to 77 conventional and experimental therapeutic agents with transcriptional, proteomic and genomic subtypes found in primary tumors. Almost all compounds produced strong differential responses across the cell lines produced responses that were associated with transcriptional and proteomic subtypes and produced responses that were associated with recurrent genome copy number abnormalities. These associations can now be incorporated into clinical trials that test subtype markers and clinical responses simultaneously. |
priorityDate |
2011-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |