| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13b7febdbf3227eb1268ad153a9c3365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06b9da69626ed1dd1f9c8b1b7447e433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9327cf5b1c428774e224958a5c590129
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_315f9ce39ec903ef501f145287089892
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c73af51e2d45af026d431c53f0eaf42a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-807
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-918
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-773
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-788 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54388
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-558 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-558 |
| filingDate |
2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbec36650bca937941025428d996c392
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70bf1a94519119ae442fe570b24a7019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08e6377b9c13984b60c6d146e8ad752b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71d2b2e02db335f4002c3928c1559f07 |
| publicationDate |
2016-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9494584-B2 |
| titleOfInvention |
Signal enhancement system with multiple labeled-moieties |
| abstract |
Dipstick tests for detecting analyte are described. In a preferred embodiment, a multiple biotinylated antibody capable of binding analyte is bound to an anti-biotin antibody labelled with colloidal gold and wicked up the dipstick with test solution thought to contain analyte. Complex formed between analyte, biotinylated anti-analyte antibody, and colloidal gold labelled anti-biotin antibody is captured at a capture zone of the dipstick. Presence of colloidal gold label at the capture zone indicates the presence of analyte in the test solution. The sensitivity of analyte detection using such methods is an order of magnitude higher than for comparable methods in which biotinylated anti-analyte antibody bound to analyte is wicked up the dipstick in a first step, and a colloidal gold labelled anti-biotin antibody is wicked up the dipstick in a separate step. Kits for performing the tests of the invention are also described. |
| priorityDate |
2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |