| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91caeb57744ca0c59ea8fa10d91d9daf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b5105ab61c89f705cd1a33d1431adf6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84498ee3a3aff5b465695c063b71690b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35baa5e56b00925eb8e21a61bb61c76a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-208 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2010-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9e1b9b00407c4ef9558e10d5e9d627a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78a4525ac357d2ae92020fb064397234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb7651a45c7a58c6fc0b531b179b7e16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf62612bdfcb25e78cf411d197acb039 |
| publicationDate |
2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9488644-B2 |
| titleOfInvention |
Assays for determining the effect of an immune cell on a cell from an infectious or neoplastic disease |
| abstract |
An in vitro assay is provided for determining the effect of an immune cell on a cell from an infectious or neoplastic disease. Also provided is an in vitro assay for determining the effect of an activated CD8 + T-cell on a sensitized melanoma cell. A method for improving the specific cytolytic activity (SCA) of an immune cell comprising contacting an immune cell with an antigen and an antigen-independent pro-inflammatory agent is provided. A method for ex vivo expansion of antigen-specific CD8 + T-cells with enhanced specific cytolytic activity (SCA) comprising culturing the antigen-specific CD8 + T-cells in a suitable culture media comprising an amino acid. An in vitro assay is provided for determining the effect of an immune cell on a cell from an infectious or neoplastic disease. A method of treating a subject suffering from an infectious or neoplastic disease with immuno therapy is described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019038673-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10912798-B2 |
| priorityDate |
2009-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |