| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c590f152de26986e186f07ee0a19a13e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc5cfffdb87976fd8d012b18b3dba77f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0328b29272d69ccbbd657dba6ac5d8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f2801557ee8a3d533222b3b8144b5b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72fb7966c2b9de9cb554e7f28a1f2f48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14351992ebda6129c20209da69633b84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c24eb7f736c09f59fa36a1b8c922d0a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16722 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-21 |
| filingDate |
2006-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be64b12007df25ce8ecdba9aa9a7ccf2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a24bde7df503a0384c5006eb5cf37f4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4bd37a50dd9a5d4370c4b3e3b2f3bdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad3eb4ae6aa23004815118c9a0ada29e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4934fb7bac812e2a4a9f8f16a82c4662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_052cfb5034eef0affd36b1fd48b51198 |
| publicationDate |
2016-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9474793-B2 |
| titleOfInvention |
Vaccines and methods for prevention and treatment of drug-resistant HIV-1 and hepatitis B virus |
| abstract |
The present invention provides methods for lowering a viral load of a virus resistant to an antiviral drug by inducing cytotoxic T lymphocytes (CTL) to recognize a predetermined mutated epitope within a viral protein of the drug-resistant virus. CTLs are induced by immunizing a host with a peptide comprising the predetermined mutation. The immunostimulating peptide may be further improved by epitope-enhancement for inducing specific CTLs. The antiviral protection against drug-resistant virus shown by compositions of the present invention and mediated by human HLA-restricted CTL has not been previously achieved. |
| priorityDate |
2005-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |