Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7911fe680008f4db27df32a1be371089 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B29-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B7-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C30B29-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C30B7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C30B7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 |
filingDate |
2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e4b19b03ac19c0b62c685a157c152f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8b7a40953308e0d3988d67906d33ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c4670a65298b4c143e98252e7c1fa87 |
publicationDate |
2016-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9458149-B2 |
titleOfInvention |
Crystal form of dabrafenib and preparation method and use thereof |
abstract |
The invention relates to Crystal Form VII of dabrafenib and preparation method thereof, wherein Crystal Form VII has the advantage of being more stable at room temperature or in aqueous systems, and has low hygroscopicity, and thus is more suitable for a wet granulation process or being prepared into a suspension; and the present invention also relates to a pharmaceutical composition and formulations comprising Crystal Form VII, and their use in the treatment of Raf family kinase-related diseases. |
priorityDate |
2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |