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filingDate 2015-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c6bf164a2fcba71d8e7307ca7a7447d
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publicationDate 2016-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9452200-B2
titleOfInvention Activators of CXCR3 for the treatment of angiopathies of the eye
abstract The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or diabetic retinopathy, by administering an activator of C-X-C chemokine receptor 3 (CXCR3). In some embodiments, the activator of CXCR3 is interferon-γ-inducible 10 kDa protein (IP-10) or a fragment or variant thereof, such as a fragment comprising or consisting of the C-terminal α-helix of IP-10. In other embodiments, the activator of CXCR3 is platelet factor 4 (PF4) or a fragment or variant thereof.
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