Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f50ff908b1e27ef37a145df93b6f4cd1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe557ffef119de98ac130a7b1c7859b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc7693dae06e6b3ff39c820ec91bf5db http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35d9ddd9f56e7f62be5d219a16cc62e4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-174614 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-493 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0036 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09G5-00 |
filingDate |
2008-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_099eebee1d8b2f9d46e1edf98656a7a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fbc9c0459f2bf5270d8cad70f444dd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_665cadea22b187e9f124e8d767b45f57 |
publicationDate |
2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9423405-B2 |
titleOfInvention |
Trimethylamine compounds as risk predictors of cardiovascular disease |
abstract |
Methods of characterizing a test subject's risk of having or developing cardiovascular disease are provided. The methods include using an analytic device to determine levels of choline-related trimethylamine-containing compounds such as trimethylamine N-oxide, choline, or betaine in a biological sample obtained from the subject and comparing the levels of the choline-related trimethylamine-containing compound in the subject's biological sample to a control value. The test subject's risk of having cardiovascular disease is then characterized as higher if the levels of the choline-related trimethylamine-containing compound are higher than the control value. Also provided are methods of identifying a subject at risk of experiencing a complication of atherosclerotic cardiovascular disease, and methods of evaluating the efficacy of a cardiovascular therapeutic agent in a subject with cardiovascular disease using levels of choline-related trimethylamine-containing compounds. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10551372-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016349236-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020173979-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10213407-B2 |
priorityDate |
2007-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |