| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e72cccf41f0b6a4dfe2745d6a0153d01 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0818
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-081 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 |
| filingDate |
2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_212e8743216f8c10d15fe68dd39306d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a912f65f2205b3f3862879a81486b602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40fe236512041800ea16ec56b16bbdaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56fe9f9ea6efe6e1d0220129d5c1ee05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1f149c1a95098c96fbc3a71bb2159cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d24e372e5095bf85da4e41fea178de64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd678fe5b2a4a95e38308a77c33e6b4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c4f20f09d30f69ace45c21b5330d8e4 |
| publicationDate |
2016-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9409928-B2 |
| titleOfInvention |
Aggregation induced emission active cytophilic fluorescent bioprobes for long-term cell tracking |
| abstract |
Fluorescent bioprobes comprising luminogen formed nanoparticles comprising luminogens with aggregation-induced emission (AIE) properties, which can be used for long-term cell tracking. The luminogens are nonemissive in organic solution but become highly emissive when aggregated in aqueous solution. The fluorescent molecules can readily pass through cell membranes, stain only the cell cytoplasm, and form highly emissive nanoaggregates in aqueous media without any obvious cytoxicity in the living cells. Furthermore, the molecules can be retained inside the cells without noticeable leakage to the outside. Therefore, these AIE-based compounds can be used as selective and cell-compatible fluroescent bioprobes for long-term live cell tracking and imaging. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018146534-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9618453-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013266953-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10139389-B2 |
| priorityDate |
2011-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |